Téléchargez le livre : Systems Analysis of Chromatin-Related Protein Complexes in Cancer

Systems Analysis of Chromatin-Related Protein Complexes in Cancer



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Springer


Paru le : 2013-08-13



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Description

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Epigenetic modifications underlie all aspects of human physiology, including stem cell renewal, formation of cell types and tissues. They also underlie  environmental impacts on human health, including aging and diseases like cancer. Consequently, cracking the epigenetic "code" is considered a key challenge in biomedical research.

Chromatin structure and function are modified by protein complexes, causing genes to be turned “on” or “off” and controlling other aspects of DNA function. Yet while there has been explosive growth in the epigenetics field, human chromatin-modifying machines have only recently started to be characterized.

To meet this challenge, our book explores complementary experimental tracks, pursued by expert international research groups, aimed at the physical and functional characterization of the diverse repertoire of chromatin protein machines  - namely, the "readers, writers and erasers" of epigenomic marks. These studies include the identification of RNA molecules and drugs that interact selectively with components of the chromatin machinery.

What makes this book distinctive is its emphasis on the systematic exploration of chromatin protein complexes in the context of human development and disease networks.
Pages
316 pages
Collection
n.c
Parution
2013-08-13
Marque
Springer
EAN papier
9781461479307
EAN EPUB
9781461479314
Informations sur l'ebook
Nombre pages copiables
3
Nombre pages imprimables
31
Taille du fichier
3645 Ko
Ce livre est accessible aux handicaps Voir les informations sur l'accessibilité
Prix
147,69 €

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