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Louise Reader

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Description

This book provides a timely review of the role of histone modifications in epigenetic control of gene expression. Topics covered include: basic mechanisms of molecular recognition of histone post-translational modification (PTMs); combinatorial readout of histone PTMs by tandem epigenome reader domains; genome-wide profiling of histone PTM interactions; small molecule modulation of histone PTM interactions and their potential as a new approach to therapeutic intervention in human diseases. All chapters were written by leading scientists who made the original key discoveries of the structure and mechanism of evolutionarily conserved reader domains, which serve to direct gene transcription in chromatin through interactions with DNA-packing histones in a PTM-sensitive manner.
Pages
282 pages
Collection
n.c
Parution
2015-05-29
Marque
Springer
EAN papier
9783319181011
EAN PDF
9783319181028

Informations sur l'ebook
Nombre pages copiables
2
Nombre pages imprimables
28
Taille du fichier
9554 Ko
Prix
94,94 €
EAN EPUB
9783319181028

Informations sur l'ebook
Nombre pages copiables
2
Nombre pages imprimables
28
Taille du fichier
4147 Ko
Prix
94,94 €

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