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Description
Transcription, or the process by which DNA produces RNA, is a central aspect of gene expression. Transcription factors regulate transcription during development and in disease states. As such, it is critical for researchers to gain a good understanding of the relationship between the structure of various families of transcription factors and their function, as well as roles in human disease. Since publication of the Fourth Edition, there have been major advances, notably in the areas of chromatin remodeling and genome-scale analyses. This complete update includes all new coverage of the latest developments, from enabling genomic technologies to studies on the importance of post-translational modifications beyond phosphorylation events. - Potential of transcription factors as therapeutic targets in human disease - Importance of histone modifications - Use of genome-based sequence analysis and high-throughput methods - Applications of the chromatin immunoprecipitation (ChIP) assay - Transcriptional elongation - Regulation by post-translational modifications - Regulatory networks and bioinformatics
Pages
488 pages
Collection
n.c
Parution
2010-07-28
Marque
Academic Press
EAN papier
9780123739834
EAN PDF
9780080561035

Informations sur l'ebook
Nombre pages copiables
48
Nombre pages imprimables
48
Taille du fichier
13148 Ko
Prix
70,63 €
EAN EPUB SANS DRM
9780080561035

Prix
70,63 €

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