Téléchargez le livre : Design and Optimization in Organic Synthesis

Design and Optimization in Organic Synthesis



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Éditeur :

Elsevier Science


Paru le : 1991-11-21



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Description
This is the first general textbook on experimental design and optimization in organic synthesis. The book presents a unified methodology for carrying out systematic studies when the objective is to develop efficient and optimum synthetic methods. Strategies are included both for exploring the experimental conditions and for systematic studies of entire reaction systems (substrates, reagent(s) and solvents). The methodology is based on multivariate statistical techniques.


The following topics are treated in depth: classical two-level designs for screening experiments, gradient methods (steepest ascent, simplex methods) as well as response surface techniques for optimization, principal components analysis and PLS modelling.


The book is intended as a hands-on text for chemists and engineers engaged in developing synthetic methods in industrial research, e.g. in fine chemicals and pharmaceuticals production, as well as for advanced undergraduate students, graduate students, and researchers in an academic environment.
Pages
552 pages
Collection
n.c
Parution
1991-11-21
Marque
Elsevier Science
EAN papier
9780444892010
EAN PDF
9780080868356
Informations sur l'ebook
Nombre pages copiables
55
Nombre pages imprimables
55
Taille du fichier
17910 Ko
Ce livre est accessible aux handicaps Voir les informations sur l'accessibilité
Prix
57,97 €

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