Téléchargez le livre : Neurodegeneration

Neurodegeneration

The Molecular Pathology of Dementia and Movement Disorders

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Wiley-Blackwell


Paru le : 2011-09-09



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Description
Most textbooks on neurodegenerative disorders have used a classification scheme based upon either clinical syndromes or anatomical distribution of the pathology.  In contrast, this book looks to the future and uses a classification based upon molecular mechanisms, rather than clinical or anatomical boundaries.  Major advances in molecular genetics and the application of biochemical and immunocytochemical techniques to neurodegenerative disorders have generated this new approach. Throughout most of the current volume, diseases are clustered according to the proteins that accumulate within cells (e.g. tau, a-synuclein and TDP-43) and in the extracellular compartments (e.g. ß-amyloid and prion proteins) or according to a shared pathogenetic mechanism, such as trinucleotide repeats, that are a feature of specific genetic disorders. Chapters throughout the book conform to a standard lay-out for ease of access by the reader and are written by a panel of International Experts Since the first edition of this book, major advances have been made in the discovery of common molecular mechanisms between many neurodegenerative diseases most notably in the frontotemporal lobar degenerations (FTLD) and motor neuron disease or amyotrophic lateral sclerosis. This book will be essential reading for clinicians, neuropathologists and basic neuroscientists who require the firm up-to-date knowledge of mechanisms, diagnostic pathology and genetics of Neurodegenerative diseases that is required for progress in therapy and management.
Pages
496 pages
Collection
n.c
Parution
2011-09-09
Marque
Wiley-Blackwell
EAN papier
9781405196932
EAN PDF
9781444341225
Informations sur l'ebook
Nombre pages copiables
0
Nombre pages imprimables
496
Taille du fichier
51896 Ko
Ce livre est accessible aux handicaps Voir les informations sur l'accessibilité
Prix
257,37 €
EAN EPUB
9781444341232
Informations sur l'ebook
Nombre pages copiables
0
Nombre pages imprimables
496
Taille du fichier
52767 Ko
Ce livre est accessible aux handicaps Voir les informations sur l'accessibilité
Prix
257,37 €

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